Michuda, Jackson
Breschi, Alessandra
Kapilivsky, Joshuah
Manghnani, Kabir
McCarter, Calvin
Hockenberry, Adam J.
Mineo, Brittany
Igartua, Catherine
Dudley, Joel T.
Stumpe, Martin C.
Beaubier, Nike
Shirazi, Maryam
Jones, Ryan
Morency, Elizabeth
Blackwell, Kim
Guinney, Justin
Beauchamp, Kyle A. http://orcid.org/0000-0001-6095-8788
Taxter, Timothy
Funding for this research was provided by:
Tempus Labs
Article History
Accepted: 2 April 2023
First Online: 26 April 2023
Declarations
:
: Funding for this project and open access was provided directly by Tempus Labs.
: All authors are employees, former employees, and/or hold restricted stock units of Tempus Labs, Inc.
: Raw data for this study were generated at Tempus Labs. Derived data supporting the findings of this study are available within the paper and its Supplementary Figs./Tables. Requests for additional data should be addressed to <u>publication.inquiry@tempus.com</u>. Due to the clinical nature of these samples, requests will be evaluated by a Data Access Review Group and are subject to a signed data transfer agreement.
: Analyses were performed using de-identified data under the exemption Pro00042950, granted from the Advarra, Inc Institutional Review Board (IRB) on 15 April 2020 based on the Department of Health and Human Services regulations found at “45 CFR 46.104(d)(4).” All methods were carried out in accordance with relevant guidelines and regulations. Internal validations and laboratory protocols were developed and performed in a CLIA-certified, CAP-accredited laboratory.
: Written informed consent is not required from the subject/s or legal guardians per the above-stated exemption (consent was exempted by Advarra Inc. Institutional Review Board).
: N/A.
: N/A.
: JM, AB, JK, AJH, JG, KAB, and TT conceptualized the work. BM performed wet-lab experiments. JM, KM, NB, MS, RJ, EM, KAB, and TT curated data. MB, AB, JK, KM, CM, and KAB wrote the software. JM and JK provided the formal analysis and validation. MCS, NB, MS, RJ, EM, KB, JG, KAB, and TT supervised the work. JM, KM, AJH, JG, KAB, and TT contributed to data visualization. All authors participated in drafting the manuscript. JM, JK, KM, AJH, CI, JTD, MCS, NB, JG, KAB, and TT edited the manuscript.