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Article History

Received: 30 April 2025

Accepted: 8 August 2025

First Online: 22 August 2025

Declarations

:

: No funding was received for the conduct of this study or the preparation of this manuscript.

: Emanuella M. Brito, Emma M. Baker, Nicholas Ahye, MD, Bryan Lieber, MD, Sajini Hettiarachchi, Maria J. Moreno Hollweg, Sabrin Safar, Steven Vanni, DO, and Regina M. Graham, PhD declare that they have no conflicts of interest that might be relevant to the contents of this manuscript.

: Not applicable.

: Not applicable.

: Emanuella M. Brito made substantial contributions to the conception and design of the work, drafted the manuscript, and approved the final version. Emma M. Baker and Sajini Hettiarachchi contributed to the drafting and critical revision of the manuscript and to figure development. Maria J. Moreno Hollweg and Sabrin Safar contributed to the acquisition and interpretation of relevant literature and figure preparation. Nicholas Ahye, MD, Bryan Lieber, MD, and Steven Vanni, DO, contributed to the interpretation of clinical content and critically revised the manuscript for important intellectual content. Regina M. Graham, PhD, provided supervision, critical revision of the manuscript, and final approval of the version to be published. All authors meet the ICMJE criteria for authorship, have approved the submitted version, and agree to be accountable for all aspects of the work.

: Data sharing not applicable to this article as no datasets were generated or analyzed during the current study.

: Not applicable.