Text and Data Mining valid from 2016-08-23
Received: 20 June 2016
Accepted: 7 August 2016
First Online: 23 August 2016
Compliance with ethical standards
: This study received no funding.
: Drs. Olguin, Fuentes and Gabler have no conflicts of interest to disclose. Dr. McElroy is a consultant to or member of the scientific advisory boards of Bracket, F. Hoffmann-La Roche Ltd., MedAvante, Myriad, Naurex, Novo Nordisk, Shire, and Sunovion. She is a principal or co-investigator on studies sponsored by the Alkermes, Forest, Marriott Foundation, National Institute of Mental Health, Naurex, Orexigen Therapeutics, Inc., Shire, Sunovion, and Takeda Pharmaceutical Company Ltd. She is also an inventor on United States Patent No. 6,323,236 B2, Use of Sulfamate Derivatives for Treating Impulse Control Disorders, and along with the patent’s assignee, the University of Cincinnati, Cincinnati, Ohio, has received payments from Johnson & Johnson, which has exclusive rights under the patent. Dr. Keck is employed by the University of Cincinnati College of Medicine and the University of Cincinnati Physicians. Dr. Keck is presently or has been in the past year a principal or co-investigator on research studies sponsored by: Cephalon, Marriott Foundation, National Institute of Mental Health (NIMH), Shire. Dr. Keck has been reimbursed for consulting to: 2014: Shire, Supernus, Otsuka, ProPhase, Merck. Dr. Paul E. Keck, Jr. is a co-inventor on United States Patent No. 6,387,956: Shapira NA, Goldsmith TD, Keck, PE Jr. (University of Cincinnati) Methods of treating obsessive–compulsive spectrum disorder comprises the step of administering an effective amount of tramadol to an individual. Filed March 25, 1999; approved May 14, 2002. Dr. Keck has received no financial gain from this patent. Dr. Guerdjikova is employed by the University of Cincinnati College of Medicine and is a consultant for Bracket.This is a review article. No animals were involved.This is a review article. To the best of our knowledge, all procedures performed in studies described in the review, involving human participants, were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
: This article does not contain any studies with human participants or animals performed by any of the authors.
: Informed consent was obtained from all participants.