Hezel, Natalie https://orcid.org/0000-0001-9791-966X
Buchner, Theresa https://orcid.org/0009-0002-8296-3507
Becker, Clemens https://orcid.org/0000-0003-1624-8353
Bauer, Jürgen M. https://orcid.org/0000-0001-7379-0646
Steib, Simon https://orcid.org/0000-0002-5767-8205
Werner, Christian https://orcid.org/0000-0003-0679-3227
Funding for this research was provided by:
Medizinische Fakultät Heidelberg der Universität Heidelberg
Article History
Received: 9 October 2025
Accepted: 31 December 2025
First Online: 16 January 2026
Declarations
:
: The FEATURE trial was approved by the Ethics Committee of the Medical Faculty Heidelberg (approval # S-602/2022) and conducted in accordance with the 1964 Helsinki Declaration and its later amendments. Written informed consent was obtained from all participants prior to study enrollment.
: The authors, including Clemens Becker as a member of the journal’s Editorial Board, have no competing interests to declare that are relevant to the content of this article.