Funding for this research was provided by:
Instituto de Salud Carlos III (PI13/01237)
Text and Data Mining valid from 2018-04-23
Received: 6 December 2017
Accepted: 10 April 2018
First Online: 23 April 2018
Compliance with ethical standards
: The authors declared no potential conflicts of interest with respect to the research, authorship and/or publication of this article.
: The authors declared that the manuscript has not been submitted to more than one journal for simultaneous consideration and it has not been published previously. No data have been fabricated or manipulated to support your conclusions. No data, text, or theories by others are presented as if they were the author’s own. This study is not split up into several parts to increase the quantity of submissions and submitted to various journals or to one journal over time. Consent to submit has been received explicitly from all co-authors, as well as from the hospital where the work has been carried out. All authors have contributed sufficiently to the scientific work and therefore share collective responsibility and accountability for the results.
: In this controlled study participants were voluntarily recruited and they all signed an informed consent.