Mease, Philip J. http://orcid.org/0000-0002-6620-0457
Gladman, Dafna D. http://orcid.org/0000-0002-9074-0592
Poddubnyy, Denis
Chakravarty, Soumya D. http://orcid.org/0000-0001-7957-838X
Shawi, May http://orcid.org/0000-0001-6005-3938
Kollmeier, Alexa P.
Xu, Xie L.
Xu, Stephen
Deodhar, Atul http://orcid.org/0000-0002-4195-8616
Baraliakos, Xenofon http://orcid.org/0000-0002-9475-9362
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Funding for this research was provided by:
Janssen Research and Development
Article History
Received: 16 May 2023
Accepted: 3 August 2023
First Online: 11 October 2023
Declarations
:
: Philip J. Mease has received research grants from AbbVie, Acelyrin, Amgen, Bristol Myers Squibb, Eli Lilly, Janssen, Novartis, Pfizer, SUN, and UCB; consulting fees from AbbVie, Acelyrin, Aclaris, Amgen, Boehringer Ingelheim, Bristol Myers Squibb, Eli Lilly, Galapagos, Gilead, GlaxoSmithKline, Immagene, Janssen, Novartis, Pfizer, SUN, UCB, Ventyx; speaker fees from AbbVie, Amgen, Eli Lilly, Janssen, Novartis, Pfizer, and UCB. Dafna D. Gladman has received grant support from AbbVie, Amgen, Bristol Myers Squibb, Celgene, Eli Lilly, Janssen, Novartis, Pfizer and UCB and consulting fees from AbbVie, Amgen, Bristol Myers Squibb, Celgene, Eli Lilly, Galapagos, Gilead, Janssen, Novartis, Pfizer, and UCB. Denis Poddubnyy has received consulting fees from AbbVie, Biocad, Bristol Myers Squibb, Eli Lilly, Gilead, GlaxoSmithKline, MSD, Novartis, Pfizer, Roche, and UCB and grants from AbbVie, Eli Lilly, MSD, Novartis, and Pfizer. Soumya D. Chakravarty is an employee of Janssen Scientific Affairs, LLC, and owns stock in Johnson & Johnson. May Shawi, Alexa P. Kollmeier, Xie L. Xu, and Stephen Xu are employees of Janssen Research & Development, LLC, and own stock in Johnson & Johnson. Atul Deodhar received consulting fees for participation in Advisory Boards from AbbVie, Amgen, Aurinia, Bristol Myers Squibb, Celgene, Eli Lilly, GlaxoSmithKline, Janssen, MoonLake, Novartis, Pfizer, and UCB; Research Grant funding from AbbVie, Eli Lilly, GlaxoSmithKline, Novartis, Pfizer, and UCB; and Speaker fees from AbbVie, Eli Lilly, Janssen, Novartis, Pfizer, and UCB. Xenofon Baraliakos has received consulting fees, grant/research support/speaker support from AbbVie, Biocad, Chugai, Eli Lilly, Janssen, Merck Sharp & Dohme, Novartis, Pfizer, Roche, and UCB.
: DISCOVER-1 and DISCOVER-2 were conducted in accordance with the Declaration of Helsinki and Good Clinical Practices. The protocols were reviewed and approved by an institutional review board or ethics committee at each site (Supplementary Material), and all patients gave written informed consent.