Curtis, Jeffrey R. http://orcid.org/0000-0002-8907-8976
Deodhar, Atul
Soriano, Enrique R. http://orcid.org/0000-0003-3143-1084
Rampakakis, Emmanouil
Shawi, May
Shiff, Natalie J.
Han, Chenglong
Tillett, William http://orcid.org/0000-0001-7531-4125
Gladman, Dafna D.
Funding for this research was provided by:
Janssen Research & Development, LLC
Article History
Received: 13 May 2024
Accepted: 15 July 2024
First Online: 11 September 2024
Declarations
:
: Jeffrey R Curtis: received grant/research support from AbbVie, Amgen, Bristol Myers Squibb, CorEvitas, Eli Lilly, Janssen, Myriad, Novartis, Pfizer, Sanofi, UCB, and NIAMS P30AR072583; consulting fees from AbbVie, Amgen, Bristol Myers Squibb, CorEvitas, Eli Lilly, Janssen, Myriad, Novartis, Pfizer, Sanofi, and UCB. Atul Deodhar: received consulting fees for participation in advisory boards from AbbVie, Bristol Myers Squibb, Celgene, Eli Lilly, Janssen, Novartis, Pfizer, and UCB; research grant funding from AbbVie, Eli Lilly, Novartis, Pfizer, and UCB; speaker fees from Eli Lilly, Janssen, Novartis, Pfizer, and UCB. Enrique R Soriano: speakers bureau for AbbVie, Amgen, Bristol Myers Squibb, Eli Lilly, Janssen, Novartis, Pfizer, Roche, and UCB; consulting fees from AbbVie, Janssen, Novartis, and Roche; grant/research support from AbbVie, Janssen, Novartis, Pfizer, Roche, and UCB. Emmanouil Rampakakis: consulting fees from Janssen; employee of JSS Medical Research. May Shawi: shareholder of Johnson & Johnson; employee of Janssen Research & Development, LLC. Natalie J Shiff: shareholder of AbbVie, Gilead, Iovance, Jazz Pharmaceuticals, Johnson & Johnson, Novavax, and Viatris; employee of Janssen Scientific Affairs, LLC, a Johnson & Johnson company, at the time this work was performed (current employee of Alpine Immune Sciences, a Vertex company). Chenglong Han: shareholder of Johnson & Johnson; employee of Janssen Global Services, LLC. William Tillett: received consulting fees from AbbVie, Amgen, Eli Lilly, Janssen, MSD, Novartis, Ono-Pharma, Pfizer, and UCB; grant/research support from AbbVie, Amgen, Eli Lilly, Janssen, Pfizer, and UCB; speaker fees from AbbVie, Amgen, Eli Lilly, Janssen, MSD, Novartis, Pfizer, and UCB. Dafna D Gladman: grant support from AbbVie, Amgen, Bristol Myers Squibb, Celgene, Eli Lilly, Janssen, Novartis, Pfizer and UCB; consulting fees from AbbVie, Amgen, Bristol Myers Squibb, Celgene, Eli Lilly, Galapagos, Gilead, Janssen, Novartis, Pfizer, and UCB.
: The DISCOVER-1 (NCT03162796) and DISCOVER-2 (NCT03158285) studies were conducted in accordance with the principles of the Declaration of Helsinki and International Council for Harmonization Guidelines for Good Clinical Practice. Each participating site's governing ethical body approved study protocols, and all patients provided written informed consent.