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Authors
Mease, Philip J. https://orcid.org/0000-0002-6620-0457
Warren, Richard B.
Nash, Peter
Grouin, Jean-Marie
Lyris, Nikos
Willems, Damon
Taieb, Vanessa
Eells, Jason
McInnes, Iain B.
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Clinical Trials BETA
Clinical trials referenced in this document:
nct03895203 at ClinicalTrials.govnct03896581 at ClinicalTrials.govDocuments that mention this clinical trial
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https://doi.org/10.1136/rmdopen-2024-005026
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https://doi.org/10.1007/s40744-024-00706-w
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https://doi.org/10.1136/annrheumdis-2024-eular.1239
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https://doi.org/10.1136/rmdopen-2021-002074
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https://doi.org/10.1136/rmdopen-2023-003548
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https://doi.org/10.1136/rmdopen-2024-004464
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POS0969 BIMEKIZUMAB-TREATED PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS SHOWED SUSTAINED ACHIEVEMENT OF MINIMAL DISEASE ACTIVITY AND REMISSION: UP TO 2-YEAR RESULTS FROM TWO PHASE 3 STUDIES
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Documents that mention this clinical trial
POS1545 MODULATION OF SERUM BIOMARKERS IN PATIENTS WITH PSA TREATED WITH RISANKIZUMAB IN THE PHASE 3 KEEPSAKE 2 STUDY
https://doi.org/10.1136/annrheumdis-2023-eular.3927
POS1524 DURABLE CLINICALLY-MEANINGFUL IMPROVEMENTS IN HEALTH-RELATED QUALITY OF LIFE, FATIGUE, PAIN, AND WORK PRODUCTIVITY AMONG PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS TREATED WITH RISANKIZUMAB AT WEEK 100
https://doi.org/10.1136/annrheumdis-2023-eular.3268
POS1036 EFFICACY AND SAFETY OF RISANKIZUMAB (RZB) FOR ACTIVE PSORIATIC ARTHRITIS (PsA): 52-WEEK RESULTS FROM KEEPsAKE 2
https://doi.org/10.1136/annrheumdis-2022-eular.1673
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https://doi.org/10.1136/rmdopen-2022-002286
AB0957 IMPROVEMENTS IN PATIENT-REPORTED OUTCOMES AMONG PATIENTS WITH RESOLUTION OF ENTHESITIS AND/OR DACTYLITIS: POST HOC ANALYSES FROM THE KEEPSAKE 1 AND 2 TRIALS OF RISANKIZUMAB IN PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS
https://doi.org/10.1136/annrheumdis-2023-eular.2790
Efficacy and safety of risankizumab for active psoriatic arthritis: 24-week results from the randomised, double-blind, phase 3 KEEPsAKE 1 trial
https://doi.org/10.1136/annrheumdis-2021-221019
Comparative Effectiveness of Bimekizumab and Risankizumab in Patients with Psoriatic Arthritis at 52 Weeks Assessed Using a Matching-Adjusted Indirect Comparison
https://doi.org/10.1007/s40744-024-00706-w
POS1032 RISANKIZUMAB FOR ACTIVE PSORIATIC ARTHRITIS: INTEGRATED SUBGROUP ANALYSIS FROM 2 DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE 3 STUDIES (KEEPsAKE 1 AND KEEPsAKE 2)
https://doi.org/10.1136/annrheumdis-2022-eular.1390
Enthesitis and Dactylitis Resolution with Risankizumab for Active Psoriatic Arthritis: Integrated Analysis of the Randomized KEEPsAKE 1 and 2 Trials
https://doi.org/10.1007/s13555-024-01174-4
OP0228 EFFICACY AND SAFETY OF RISANKIZUMAB FOR ACTIVE PSORIATIC ARTHRITIS, INCLUDING PATIENTS WITH INADEQUATE RESPONSE OR INTOLERANCE TO BIOLOGIC THERAPIES: 24-WEEK RESULTS FROM THE PHASE 3, RANDOMIZED, DOUBLE-BLIND, KEEPSAKE 2 TRIAL
https://doi.org/10.1136/annrheumdis-2021-eular.2695
Efficacy and safety of risankizumab for active psoriatic arthritis: 24-week results from the randomised, double-blind, phase 3 KEEPsAKE 2 trial
https://doi.org/10.1136/annrheumdis-2021-221048
Population Pharmacokinetics and Exposure–Response Analyses for Risankizumab in Patients with Active Psoriatic Arthritis
https://doi.org/10.1007/s40744-022-00495-0
AB0905 Routine Assessment of Patient Index Data 3 (RAPID3) in Patients With Active Psoriatic Arthritis (PsA) After Inadequate Response or Intolerance to DMARDs: Pooled Results From the Phase 3, Randomized, Double-Blind KEEPsAKE 1 and 2 Trials
https://doi.org/10.1136/annrheumdis-2022-eular.2913
POS1057 IMPACT OF RISANKIZUMAB ON ENTHESITIS AND ASSOCIATED PAIN: POOLED RESULTS FROM THE PHASE 3, RANDOMIZED, DOUBLE-BLIND KEEPsAKE 1 AND 2 TRIALS
https://doi.org/10.1136/annrheumdis-2022-eular.3161
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Funding
Funding for this research was provided by:
UCB Pharma
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Article History
Received: 15 June 2024
Accepted: 22 July 2024
First Online: 9 August 2024
Declarations
:
: Phillip J. Mease: Research grants from AbbVie, Acelyrin, Amgen, BMS, Celgene, Eli Lilly, Gilead, Janssen, Novartis, Pfizer, Sun Pharma and UCB Pharma; consultancy fees from AbbVie, Acelyrin, Aclaris, Amgen, Boehringer Ingelheim, BMS, Celgene, Eli Lilly, Galapagos, Gilead, GSK, Janssen, Moonlake Pharma, Novartis, Pfizer, Sun Pharma, Takeda, and UCB, and Ventyx Pharma; speakers’ bureau from AbbVie, Amgen, Eli Lilly, Janssen, Novartis, Pfizer, and UCB Pharma. Richard B. Warren: Supported by the Manchester NIHR Biomedical Research Centre; consulting fees from AbbVie, Almirall, Amgen, Arena, Astellas, Avillion, Biogen, BMS, Boehringer Ingelheim, Celgene, DICE Therapeutics, Eli Lilly, GSK, Janssen, LEO Pharma, Meiji Pharma, Novartis, Pfizer, RAPT Therapeutics, Sanofi, Sun Pharma, UCB Pharma and Union; research grants to his institution from AbbVie, Almirall, Janssen, LEO Pharma, Novartis, Pfizer, and UCB Pharma; and honoraria from AbbVie, Almirall, BMS, Eli Lilly, Galderma, Janssen and Novartis. Peter Nash: Research grants, clinical trials and honoraria for advice and lectures on behalf of AbbVie, Boehringer Ingelheim, BMS, Celgene, Eli Lilly, Galapagos/Gilead, GSK, Janssen, Novartis, Pfizer, Samsung and UCB Pharma. Jean-Marie Grouin: Consulting fees and honoraria from Acticor, Chugai, BeiGene, Inflectis, Inotrem, Ipsen, Janssen, Otsuka, SpikImm, UCB Pharma. Nikos Lyris, Damon Willems, Vanessa Taieb, Jason Eells: Employees and shareholders of UCB Pharma. Iain B. McInnes: Consulting fees and honoraria from AbbVie, AstraZeneca, BMS, Boehringer Ingelheim, Cabaletta, Causeway Therapeutics, Celgene, Evelo, Janssen, Novartis, Eli Lilly, Moonlake, and UCB Pharma; and research support from BMS, Boehringer Ingelheim, Celgene, Janssen, Novartis, and UCB Pharma.
: BE OPTIMAL and BE COMPLETE were conducted in accordance with the Declaration of Helsinki and the International Conference on Harmonisation Guidance for Good Clinical Practice. Ethical approval was obtained from the relevant institutional review boards at participating sites, and all patients provided written informed consent by local requirements. This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by any of the authors.
