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Authors
Yoshida, Seitaro
Tchakoute, Christophe Toukam
Mao, Huiyan Ashley
Wallenstein, Gene
Ross Terres, Jorge A.
Lindsay, Lisa
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Funding
Funding for this research was provided by:
F. Hoffmann-La Roche
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Article History
Received: 9 December 2025
Accepted: 2 February 2026
First Online: 28 February 2026
Declarations
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: Seitaro Yoshida is an employee and shareholder of Chugai Pharmaceutical Co., Ltd. Christophe Toukam Tchakoute, Gene Wallenstein, and Lisa Lindsay are employees of Genentech, Inc . Huiyan (Ashley) Mao is an employee and shareholder of F. Hoffmann-La Roche Ltd. Jorge A. Ross Terres is an employee of Genentech, Inc. and shareholder of F. Hoffmann-La Roche Ltd.
: This study utilized previously published clinical trial data from the LUNAR trial. As such, no new ethical approval was required for this secondary analysis. The study was performed in accordance with the Declaration of Helsinki of 1964 and its later amendments. The original clinical trial from which these data were obtained had received ethical approval from the respective institutional review boards (IRBs), and all participants had provided informed consent that included future publication of de-identified data.
