Chen, Lianzhi
Yuan, Jun
Lu, Jun
Zhou, Gengmin
Gu, Mingxi
Yang, Yuting
Chen, Chao
Chen, Jintao
Wang, Qingwen
Funding for this research was provided by:
Perpetual’s 2023 IMPACT Philanthropy Application Program (IPAP2023/1338)
Shenzhen Medical Research Fund (C2301008)
Shenzhen Medical Research Fund (C2404002)
Basic and Applied Basic Research Foundation of Guangdong Province (2023B1515230002)
Guangdong Basic and Applied Basic Research Foundation (2023B1515230002)
Treatment and Prevention Integration Project of Shenzhen Municipal Health Commission (0102018-2019-YBXM-1499-01-0414)
Sanming Project of Medicine in Shenzhen (SZSM202311030)
Article History
Received: 7 February 2026
Accepted: 21 May 2026
First Online: 13 June 2026
Declarations
Conflict of interest: All authors, including Lianzhi Chen, Jun Yuan, Jun Lu, Gengmin Zhou, Mingxi Gu, Yuting Yang, Chao Chen, Jintao Chen, Qingwen Wang, have nothing to disclose.
Ethical approval: The present study employs data from the UK Biobank study which received approval from the National Information Governance Board for Health and Social Care and the National Health Service North West Centre for Research Ethics Committee. All participants provided electronically signed informed consent when attending baseline assessment. This study has been conducted using the UK Biobank Resource under the Application Number 199603.