Farhat, Nawal http://orcid.org/0000-0003-0291-0270
Birkett, Nicholas http://orcid.org/0000-0003-4530-8095
Haddad, Nisrine http://orcid.org/0000-0002-2056-1425
Fortin, Yannick http://orcid.org/0000-0001-7300-9549
Momoli, Franco
Wen, Shi Wu http://orcid.org/0000-0002-7227-0283
Wielgosz, Andreas http://orcid.org/0000-0002-9533-7022
McNair, Doug S. http://orcid.org/0000-0003-0965-883X
Mattison, Donald R. http://orcid.org/0000-0001-5623-0874
Krewski, Daniel http://orcid.org/0000-0003-0533-5734
Funding for this research was provided by:
Canadian Institutes of Health Research - Doctoral Award
McLaughlin Center for Population Health Risk Assessment
University of Ottawa
Article History
First Online: 2 July 2020
Compliance with ethical standards
:
: DK is the Natural Sciences and Engineering Research Council of Canada Chair in Risk Science at the University of Ottawa, a peer reviewed university–industry research partnership program. DK and DRM, respectively, serve as Chief Risk Scientist and Chief Medical Officer for Risk Sciences International (RSI) (ExternalRef removed), a Canadian company established in 2006 in partnership with the University of Ottawa to provide consulting services in risk science to both public and private sector clients. To date, RSI has not conducted work on PPIs or antiplatelet agents that are the subject of the present paper. AW is a clinical cardiologist and has treated patients with cardiovascular diseases, including myocardial infarction, using PPIs and antiplatelet agents, including clopidogrel. NB has served as a consultant to RSI. NF has served as a consultant to RSI and international clients on issues unrelated to those discussed in the present paper. NH is a senior epidemiologist with the Public Health Agency of Canada working on matters unrelated to the subject of the present paper. YF, FM, SWW, DSM, and DRM have no conflicts of interest that are directly relevant to the content of this article.
: The data that support the findings of this study are available from Cerner Health Facts©. We sought permission from Cerner to perform the current study. Restrictions apply to the availability of these data, and they are not publicly available.
: This study was funded by a Canadian Institutes of Health Research (CIHR) Doctoral Research Award (to NF) and by the McLaughlin Center for Population Health Risk Assessment, University of Ottawa, Canada.