Nurmela, Veera https://orcid.org/0009-0001-1315-2420
Juntunen, Anni
Tiainen, Satu
Martikainen, Janne
Pasonen-Seppänen, Sanna
Rönkä, Aino
Funding for this research was provided by:
State Research Funding for University-level health Research, Kuopio University Hospital, Wellbeing Service County of North Savo (5654210)
Cancer Foundation of Finland
Cancer Society of North Savo (20240026)
Suomen Lääketieteen Säätiö (7074)
the Paavo Koistinen Foundation (202300011)
Article History
Accepted: 1 June 2026
First Online: 23 June 2026
Declarations
:
: AR reports personal fees for speaking at symposia or financial support for attending conferences from Amgen, Bristol-Myers Squibb, Merck, Novartis, Pfizer and Roche. ST reports personal fees for speaking at symposia, consulting or financial support for attending conferences from Astra Zeneca, BMS, Merck, MSD, Novartis, Pfizer and Roche. None of the financial support was related to the present study. All other authors declare that they have no competing interests.
: The datasets used and/or analyzed during this study are available from the corresponding author upon reasonable request.
: This study was conducted in accordance with the Declaration of Helsinki (1964). The study received ethical approval from the Medical Research Ethics Committee of Wellbeing Services County of North Savo (permission number 1482/2019) and organization-level permission from Kuopio University Hospital (research permit 5654210, 916/2022). Due to the retrospective nature of the study, the Medical Research Ethics Committee of Wellbeing Services County of North Savo waived the informed consent requirement (permission number 1482/2019).
: Not applicable.
: Because of the retrospective design of this study, informed consent was not required.
: Not applicable.
: All authors contributed to the study conceptualization and methodology. Investigation, data curation and formal analysis were performed by Veera Nurmela, Anni Juntunen and Aino Rönkä. The original draft was written by Veera Nurmela, Anni Juntunen and Aino Rönkä. All authors critically reviewed, edited and approved the final manuscript. Project was administrated and supervised by Aino Rönkä.