De Marco, Teresa https://orcid.org/0000-0003-0183-4704
Paoli, Carly J. https://orcid.org/0000-0002-1331-9462
Croteau, Nicole S. https://orcid.org/0000-0001-5017-1834
Tang, Fei
Farber, Harrison W. https://orcid.org/0000-0002-0297-7902
Funding for this research was provided by:
Johnson and Johnson
Article History
Received: 21 July 2025
Accepted: 8 August 2025
First Online: 6 September 2025
Declarations
:
: Teresa De Marco has received research grants from CareDx and Acceleron; has received consultancy fees from Aerovate, Boston Scientific, Atara, Keros, Merck, Natera, Pulnovo, Tectonic, and United Therapeutics; has participated on advisory boards or data safety monitoring boards for Kamada, Merck, Keros Therapeutics, Tectonic, and BIAL; has received honoraria for a Simply Speaking PAH CME lecture; has received support for meeting attendance from CareDx, Atara, Kamada, and United Therapeutics; and has served on an endpoint adjudication committee for Johnson & Johnson. Carly J. Paoli is an employee and stockholder of Johnson & Johnson. Nicole S. Croteau and Fei Tang were employees of Cytel at the time of this study. Cytel has received consultancy fees from Johnson & Johnson for the conduct of this study. Harrison W. Farber has received speaking honoraria from Bayer and scientific advisory board fees from Acceleron (Merck), Actelion (Janssen), Altavant, Aerami, Aerovate, Pulmovant, and United Therapeutics, and is the Adjudicator for Keros.
: As the study was retrospective and used only deidentified aggregated patient data, it was exempt from ethical or institutional review board review/approval. The Komodo Health Research Database is compliant with the Health Insurance Portability and Accountability Act of 1996. The data were used under license from Komodo.