Felizzi, Federico
Paracha, Noman
Pöhlmann, Johannes
Ray, Joshua
Article History
Accepted: 7 February 2021
First Online: 26 February 2021
Declarations
:
: All data used in this tutorial were simulated, so no ethics approval/consent was required.
: Not applicable.
: The datasets and code generated and/or analyzed for this tutorial are available under a CC BY-NC 4.0 license on GitHub, at ExternalRef removed. The repository with the freely available commented code can be found at ExternalRef removed.
: JR is an employee of F. Hoffmann-La Roche, which develops and markets pharmaceutical products in oncology, including vemurafenib and cobimetinib, which are used as examples in this tutorial. JP was an employee of Ossian Health Economics and Communications, which received consulting fees from F. Hoffmann-La Roche to support the preparation of this tutorial. NP and FF were employees of F. Hoffmann-La Roche. The authors declare that they have no other competing interests.
: The study was conducted by the authors as part of their salaried employment. No additional funding was obtained.
: FF, NP, and JR conceived the idea of developing a tutorial on mixture cure models. FF planned the overall structure of the manuscript, developed the methodology, analyzed the data, and wrote the R code. JP drafted the manuscript and contributed to the interpretation of results and code review. NP and JR provided clinical input on melanoma and revised the manuscript critically for important intellectual content. All authors gave final approval of the version to be published and agreed to be accountable for all aspects of the work.