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Article History

Accepted: 6 October 2024

First Online: 19 November 2024

Declarations

:

: Funding was provided through a partnership grant between Alberta Innovates, Alberta Health Services, and bioMérieux. The investigators designed the study, wrote the manuscript, and vouch for the accuracy and completeness of the data and analyses. The funding organizations and partners were not involved in implementation or management of the study, in the analysis of data, or in the decision to submit the manuscript for publication.

: Jeff Round is an editorial board member of <i>PharmacoEconomics Open</i>. He was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions. John Conly was an invited speaker at a symposium on antimicrobial resistance co-hosted by the University of Toronto and bioMérieux Canada in 2022. All other authors have no relevant conflicts to declare.

: The data that support the findings of this study are available upon reasonable request if permitted by Alberta Health Services; restrictions may apply. The anonymized model is publicly available on request.

: The study was approved by the Institutional Review Boards (IRBs) at the University of Alberta (Pro00101420) and the University of Calgary (REB17-2244). Individual patient consent was waived by both IRBs given the study was classified as a quality improvement initiative.

: Not applicable.

: The decision tree model was conducted using TreeAge software and the statistical analysis was conducted in R. Both files are included as supplementary material.

: Conceptualization: C.D., D.Z., D.O., J.M.C., J.C., S.B., J.R., V.L., W.S. Data curation: K.C., C.B., M.G., C.C., T.D., C.P., A.T., D.G., D.O., J.M.C., J.C., K.F., W.S. Formal Analysis: X.W., C.Y., C.D., D.O., J.M.C., J.C., S.B., J.R., V.L., W.S. Funding acquisition: D.Z., D.O., S.B., W.S. Investigation: K.C., C.B., M.G., C.C., T.D., C.P., C.Y., G.C., A.T., D.G., C.D., D.Z., D.O., J.M.C., J.C., K.F., J.R., V.L., S.B., W.S. Methodology: X.W., C.Y., G.C., C.D., J.M.C., J.C., S.B., J.R., V.L., W.S. Project administration: D.Z., D.O., S.B., W.S. Resources: D.Z., D.O., S.B., W.S. Software: D.O., J.C., X.W. Supervision: S.B., W.S. Validation: S.B., W.S. Visualization: S.B., W.S. Writing—original draft: C.Y., C.D., J.M.C., S.B., J.R., V.L., S.B., W.S. Writing—reviewing and editing: K.C., C.B., M.G., C.C., T.D., C.P., C.Y., G.C., A.T., D.G., C.D., D.Z., D.O., J.M.C., J.C., K.F., J.R., V.L., S.B., W.S.