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Authors
Briggs, Andrew H. https://orcid.org/0000-0002-0777-1997
Chalet, François-Xavier
Cooper, Jacie
Graham, Peter
Palmer, Stephen
Miller, Paul
Walker, Andrew
Greenwood, Berkeley
Morin, Charles M.
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Funding
Funding for this research was provided by:
Idorsia Pharmaceuticals
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Article History
Accepted: 11 February 2025
First Online: 28 March 2025
Declarations
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: This study was funded by Idorsia Pharmaceuticals Ltd.
: AB, AW and BG have received consultancy payments from Idorsia Pharmaceuticals in relation to the work reported here. F-XC and PG were employees of Idorsia Pharmaceuticals at the time of conducting the work. JC is an employee of Avalon Health Economics which was compensated by Idorsia Pharmaceuticals for completion of this work. SP has received a personal honorarium payment from Idorsia Pharmaceuticals for participation in a related advisory board meeting. PM has no conflicts of interest to declare. CMM received research grants from Eisai, Idorsia, and Lallemand Health and served as consultant for Idorsia and Haleon. He received royalties from Mapi Research Trust.
: In addition to Idorsia’s existing clinical trial disclosure activities, the company is committed to implementing the Principles for Responsible Clinical Trial Data Sharing jointly issued by the European Federation of Pharmaceutical Industries and Associations (EFPIA) and the Pharmaceutical Research and Manufacturers of America (PhRMA). Requests for data sharing of any level can be directed to clinical-trials-disclosure@idorsia.com for medical and scientific evaluation. The NHWS is a commercial dataset. Access to the dataset used in this present paper must be requested to Cerner Enviza via the following link: . Data access conditions will be detailed by the responsible team.
: Not applicable.
: Not applicable.
: Not applicable.
: The model that forms the basis of this manuscript is available through the GitHub repository: under Creative Commons License: Attribution-NonCommercial-ShareAlike 4.0 International.
: The underlying model reported in this manuscript was conceived and developed by AB, FXC, JC, and PG. SP, PM, AW, and BG critical evaluated the model’s design. AB drafted the first version of the manuscript, which was reviewed and edited by all authors for scientific content. All authors approved the final version, each of whom has met the requirements for authorship.
