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Authors
Heuser, Carolina https://orcid.org/0009-0004-1454-4110
Gould, Michael K.
Choman, Eran
Olghi, Nicolò
Ogale, Sarika
Obradovic, Milan
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Funding
Funding for this research was provided by:
Genentech
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Article History
Received: 5 April 2025
Accepted: 24 November 2025
First Online: 18 December 2025
Declarations
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: MKG reports research funding from F. Hoffmann-La Roche Ltd; EC reports employment from F. Hoffmann-La Roche, which received research funding for this project from the study sponsor; NO reports employment/stockholdings for F. Hoffmann-La Roche Ltd; MO reports employment/stockholdings for F. Hoffmann-La Roche Ltd; SO reports employment/stockholdings for Genentech, the study sponsor; CHS reports employment/stockholdings for F. Hoffmann-La Roche Ltd.
: Not applicable.
: Not applicable.
: Not applicable.
: Formulae used in this model may be available to qualified researchers upon reasonable request.
: All data supporting the findings of this study are available within the paper and its supplementary information.
: All authors contributed to the study design, interpretation of findings, critical review and revision of the manuscript, and approval of the manuscript for submission; CH, EC, NO, SO, and MO also contributed to acquisition of data, data analysis, and project management.
