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Authors
Hurrell, Alice https://orcid.org/0000-0002-5870-7629
Webster, Louise
Sparkes, Jenie
Battersby, Cheryl
Clark, Katherine
Duhig, Kate E
Green, Marcus
Seed, Paul T
Vowles, Zoe
Myers, Jenny
Shennan, Andrew H
Chappell, Lucy C
Hunter, Rachael M
,
Gill, Carolyn
McDonnell, Sian
Peers, Beth
Yulia, Angela
Ferry, Orla
Maher, Martin
Pickering, Francis
Smith, Annabel
Thompson, Hilary
Basak, Sambita
Dudgeon, Lucy
Ficquet, Jo
Rich, Mel
O’Brien, Clare
Willson, Seren
Chados, Nikolaos
Bishop, Linda
Bahl, Rachna
Smart, Brittany
Arya, Rita
Roughley, Lindsay
Mehta, Anku
Campbell, Deniesha
Girling, Jo
Ryan, Grace
Trepte, Lauren
Biswas, Chandrima
Obiozo, Chinwe
Verghese, Lynda
Ahuja, Ashwin
Davies, Sarah
Morris, Katie
Davison, Jessica
Regan, Maeve
Barry, Natalie
McBean, Mel
Jennings, Jacqui
Sharp, Andrew
Holt, Siobhan
Stirrat, Laura
Jack, Elaine
Bapir, Mihraban
Gowans, Sharon
Alexander, Hazel
Hinshaw, Kim
Hewitt, Lesley
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Funding
Funding for this research was provided by:
Tommy's (80)
Jon Moulton Charity Trust (80)
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Article History
Received: 23 June 2025
Accepted: 26 November 2025
First Online: 6 January 2026
Declarations
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: AHS has received funds from Perkin Elmer (Revvity) and QuidelOrtho for expenses for meetings and has received money from Roche as a consultant on strategy. All remaining authors declare no competing interests.
: The dataset will be available to appropriate academic parties on request from the Chief Investigator (LCC) in accordance with the data sharing policies of King’s College London, with input from the co-investigator group where applicable.
: Ethical approval was from the Cambridge East Research Ethics Committee (ref. 19/EE/0322). The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and later amendments.
: Women provided written, informed consent to participate in the trial.
: AHS, LCC, and RMH conceived the study. LW, KED, JM, CB, PTS, KC, MG, AHS, and LCC were involved in securing funding for the study. AH, JS, LW, ZV and LCC coordinated the study conduct and data collection. RMH, AH, and PTS did the study analyses, supervised by LCC. RMH did the health economic analysis. RMH, AH, LW, and LCC wrote the article, with assistance from JS, KED, PTS, JM, CB, KC, ZV, and AHS. All authors approved the final version of the manuscript.
: All participants gave written informed consent for publication of trial results.
: The code will be available to appropriate academic parties on request from the Chief Investigator (LCC) in accordance with the data sharing policies of King’s College London.
