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Article History

Received: 2 September 2025

Accepted: 21 April 2026

First Online: 18 June 2026

Declarations

Conflicts of Interest: The authors, Fredrik Holmboe and Magnus Bangum, report employment with AbbVie and contributed to this methodological work in an academic capacity. No other competing interests were declared. All remaining authors claimed that there were no conflicts of interest.

Ethics Approval: Not applicable. Ethics approval was not required for this study because it was based on publicly available data and structured expert elicitation with clinicians, and did not involve patient-level identifiable data.

Consent to Participate: Not applicable.

Consent for Publication: Not applicable.

Code Availability: The R code file is available in the supplementary material of this article.

Authors’ Contributions: Yancy S. Wu: conceptualization, methodology, software, formal analysis, investigation, writing—original draft, visualization. Emily A. Burger: conceptualization, methodology, writing—review and editing, visualization, supervision, project administration. Fredrik Holmboe: conceptualization, methodology, software, writing—review and editing, supervision. Magnus Bangum: Methodology, software, writing—review and editing. Francisco Oteiza: Data curation, writing—review and editing, funding acquisition. Christoffer Bugge: Conceptualization, data curation, writing—review and editing, funding acquisition. Erik Magnus Sæther: Data curation, writing—review and editing, funding acquisition. Eline Aas: Conceptualization, methodology, writing—review and editing, supervision, project administration, funding acquisition.