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Article History

Received: 24 November 2017

Accepted: 2 March 2018

First Online: 19 March 2018

Compliance with ethical standards

:

: GDG, ADP, RSO and MD are employees of the GSK group of companies. ADP, RSO and MD hold restricted shares in the GSK group of companies. MC received personal fees from the GSK group of companies. JEM is an employee of The Health Sciences North Research Institute and her institution received an honorarium from the GSK group of companies for her attendance at an advisory board meeting and she received travel reimbursement during the conduct of this work and outside this work. PHL, BGL and JF have nothing to disclose. EW received consulting fees from Alios Pharmaceuticals outside this work. JG received grants from NIH during the conduct of this work and received personal fees from the GSK group of companies for his attendance at an advisory board meeting during the conduct of this work. SM received personal fees from the GSK group of companies for her participation in a vaccine workshop in Brussels, Belgium, in February 2016 outside this work and received a grant from Takeda outside this work. WS received a grant from Centers for Disease Control and Prevention during the conduct of this work. WS also received personal fees from Merck, Pfizer, Genentech, Dynavax and Novavax during the conduct of this work. HN received personal fees from the GSK group of companies for his attendance at an advisory board meeting during the conduct of this work and received personal fees from Pfizer and MSD outside of this work.

: All procedures performed in this study were in accordance with the ethical standards.

: For a literature review, written consent is not required.