Bath, Philip M. http://orcid.org/0000-0003-2734-5132
Skinner, Cameron J. C.
Bath, Charlotte S.
Woodhouse, Lisa J.
Korovesi, Anastasia Areti Kyriazopoulou
Long, Hongjiang
Havard, Diane
Coleman, Christopher M.
England, Timothy J.
Leyland, Valerie
Lim, Wei Shen
Montgomery, Alan A.
Royal, Simon
Avery, Amanda
Webb, Andrew J.
Gordon, Adam L.
,
Funding for this research was provided by:
NIHR Nottingham Biomedical Research Centre (/)
NIHR Senior Investigator Award (NF-SI-0515-10044)
Article History
Received: 6 August 2022
Accepted: 31 October 2022
First Online: 16 November 2022
Declarations
:
: AJW holds shares in HeartBeet Ltd, which receive a royalty from James White Drinks Ltd who manufacture the active nitrate-containing beetroot juice and placebo nitrate-depleted juice used in this study. The remaining authors declare no competing interests.
: All methods were carried out in accordance with relevant guidelines and regulations. Approvals were sought via the UK Integrated Research Application System (IRAS project 288542), and favourable opinions received from Research Ethics Committee (West Midlands: Coventry & Warwickshire Research Ethics Committee—20/WM/0278, 19/11/20) and Health Research Authority (25/11/20). Approval from the UK Medicines and Healthcare products Regulatory Agency was not sought since beetroot juice is a food.
: Written informed electronic consent (using the REDCap facility) was sought from residents if they had mental capacity to provide consent or from a family member consultee for residents who lacked capacity.
: Not applicable.