Gravett, Stephanie
Garcia-Ptacek, Sara
Rennie, Anna
Bogdanovic, Nenad
Bonnard, Alexandre
Granberg, Tobias
Nordberg, Agneta
Jelic, Vesna
Ferreira, Daniel https://orcid.org/0000-0001-9522-4338
Funding for this research was provided by:
Vetenskapsrådet (2022-00916)
Center for Innovative Medicine (20200505)
Center for Innovative Medicine (FoUI-988826)
regional agreement on medical training and clinical research of Stockholm (FoUI-962240)
regional agreement on medical training and clinical research of Stockholm (FoUI-987534)
Hjärnfonden (FO2023-0261)
Hjärnfonden (FO2022-0175)
Hjärnfonden (FO2021-0131)
Alzheimerfonden (AF-968032)
Alzheimerfonden (AF-980580)
Alzheimerfonden (AF-994058)
Alzheimerfonden (AF-1010553)
Demensfonden
Stiftelsen för Gamla Tjänarinnor
Gun och Bertil Stohnes Stiftelse
Åke Wiberg Stiftelse
StratNeuro
Parkinsonfonden
Funding for research from Karolinska Institutet
Neurofonden
Foundation for Geriatric Diseases at Karolinska Institutet
contributions from private bequests and academic agreements with industry
Karolinska Institute
Article History
Received: 5 August 2025
Revised: 25 November 2025
Accepted: 26 November 2025
First Online: 8 December 2025
Declarations
:
: DF consults for BioArctic and has received honoraria from Esteve Pharmaceuticals S.A. All other authors declared no competing interests.
: Data has been handled in accordance with GDPR legislation. The study was approved by the Regional Ethics Committee in Stockholm (Dnr: 2013/2169–31) and the following amendments were approved by the Swedish Ethical Review Authority, Uppsala (Dnr: 2019-05978, and 2022-01251-02). This study was carried out in compliance with the Declaration of Helsinki.
: All included patients provided signed written consent.
: Not applicable.