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Article History

Received: 3 July 2024

Accepted: 12 December 2024

First Online: 18 December 2024

Declarations

:

: The entire database used in this study was obtained from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database. According to ADNI protocols, all procedures conducted in studies involving human participants were based on Good Clinical Practice guidelines in accordance with the ethical standards of the institutional and/or national research committee and with the Helsinki Declaration US 21CFR Part 50 - Protection of Human Subjects, and Part 56 - Institutional Review Boards (IRBs) / Research 39 Ethics Boards (REBs), pursuant to state and federal HIPAA regulations, and its later amendments or comparable ethical standards. Written informed consent was obtained from all subjects and/or their authorized representatives and study partners before performing the protocol-specific procedures. More details are accessible at , , . The database procedures were approved by the institutional review boards of all participating centers . Ethics approval was secured from the institutional review boards of each involved institution including: the University of Southern California; Baylor College of Medicine; Johns Hopkins University; University of Michigan; Columbia University Medical Center; Oregon Health and Science University; Mayo Clinic, Rochester; Washington University, St. Louis; New York University; University of Alabama at Birmingham; University of California-San Diego; Mount Sinai School of Medicine; Rush University Medical Center; Wien Center; Duke University Medical Center; University of Kentucky; University of Pittsburgh; University of Texas Southwestern Medical School; University of Rochester Medical Center; University of California, Irvine; University of Pennsylvania; Emory University; University of Kansas, Medical Center; University of California, Los Angeles; Mayo Clinic, Jacksonville; Indiana University; Yale University School of Medicine; McGill University, Montreal-Jewish General Hospital; Sunnybrook Health Sciences, Ontario; U.B.C. Clinic for AD and Related Disorders; Cognitive Neurology-St. Joseph’s, Ontario; Cleveland Clinic Lou Ruvo Center for Brain Health; Northwestern University; Premiere Research Inst (Palm Beach Neurology); Georgetown University Medical Center; Brigham and Women’s Hospital; Stanford University; Howard University; Ohio State University; Parkwood Hospital; Wake Forest University Health Sciences; Boston University; Banner Sun Health Research Institute; University of California, Davis-Sacramento; Neurological Care of CNY; University of Wisconsin; University of California, Irvine-BIC; Banner Alzheimer’s Institute; Dent Neurologic Institute; Case Western Reserve University; Albany Medical College; Hartford Hospital, Olin Neuropsychiatry Research Center; Dartmouth-Hitchcock Medical Center; Rhode Island Hospital; Butler Hospital; UC San Francisco; Medical University South Carolina; University of Iowa College of Medicine; St. Joseph’s Health Care Nathan Kline Institute; Cornell University and University of South Florida: USF Health Byrd Alzheimer’s Institute. The investigators involved in ADNI contributed to the design and implementation of ADNI and/or provided data but they did not take part in the analysis or the writing of this paper. A comprehensive list of ADNI investigators is available at the (This article does not include any studies involving human participants conducted by the authors).

: The entire database used in this study was obtained from the Alzheimer’s Disease Neuroimaging Initiative (ADNI) database. According to ADNI protocols, all procedures conducted in studies involving human participants were based on Good Clinical Practice guidelines in accordance with the ethical standards of the institutional and/or national research committee and with the Helsinki Declaration US 21CFR Part 50 - Protection of Human Subjects, and Part 56 - Institutional Review Boards (IRBs) / Research 39 Ethics Boards (REBs), pursuant to state and federal HIPAA regulations, and its later amendments or comparable ethical standards. Written informed consent was obtained from all subjects and/or their authorized representatives and study partners before performing the protocol-specific procedures. More details are accessible at , , . The database procedures were approved by the institutional review boards of all participating centers (This article does not include any studies involving human participants conducted by the authors).

: Not applicable

: The authors have declared that no Conflict of interest exist