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Perillaldehyde Attenuates Insulin Resistance and High Glucose-Induced Ferroptosis in Trophoblast Cells via Regulation of PTPN1/Akt/Foxo1 Signaling Pathway

Crossref DOI link: https://doi.org/10.1007/s43032-025-02008-0

Published Online: 2025-10-27

Published Print: 2025-11

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wang, Xing

Lu, Yu

Wang, Suyu

Wang, Xueqin

Yang, Shufang

Zhao, Chengyuan https://orcid.org/0009-0004-0938-1468
Funding

Funding for this research was provided by:

Innovative Research Group Project of the National Natural Science Foundation of China (81900664)

Six Talent Peaks Project in Jiangsu Province (WSN-336)

Scientific Research Project of Health Commission in Jiangsu Province (LGY2020067)

Scientific Research Project, Taizhou School of Clinical Medicine, Nanjing Medical University (TZKY20220110)
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Article History

Received: 20 May 2025

Accepted: 13 October 2025

First Online: 27 October 2025

Declarations

:

: This is an in vitro investigation with the HTR-8/SVneo trophoblast cell line. The Research Ethics Committee of Affiliated Hospital 2 of Nantong University has confirmed that no ethical approval is required.

: There are no conflicts of interest to declare.

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