Kim, Ju Gyeong
Bak, Su-Bin
Kim, Gyoung-Deuck
Choi, Han-Sol
Kwon, Da-Ae
Kim, Ha-Young
Son, Dong-Won
Jeong, Jang-Hun
Lee, Byung-Woo
An, Hyo-Jin
Lee, Hak Sung http://orcid.org/0000-0001-9594-7173
Article History
Received: 23 January 2024
Revised: 12 June 2024
Accepted: 21 June 2024
First Online: 16 August 2024
Declaration
:
: All toxicity studies were conducted under GLP compliance. The authors declare that they have no conflict of interest.
: The acute oral dose study using rats was conducted with prior approval of Institutional Animal Ethics Committee (IAEC) (IAEC approval No. LN/IAEC/TOX/LN220309 and 26.03.2022.). The 4-week repeated dose study using rats was con-ducted with prior approval of Institutional Animal Ethics Committee (IAEC) (IAEC approval No. LN/IAEC/TOX/LN220306 and LN/IAEC/TOX/LN220307). The 13-week repeated dose study using rats was reviewed and approved by the Institutional Animal Care and Use Committee (IACUC) of Biotoxtech Co., Ltd. based on Animal Protection Act of Republic of Korea (Revision Feb. 11, 2020, No.16977) (Approval No.: 220211). Mammalian bone marrow erythrocyte micronucleus test was conducted with prior of Institutional Animal Ethics Committee (IAEC) (IAEC approval No. LN/IAEC/TOX/LN220301 and 26.09.2022.).