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Authors
Fagundes, Aécio C. https://orcid.org/0000-0001-6987-6340
Hansel, Gisele https://orcid.org/0000-0001-5048-1293
Souza, Diogo O. https://orcid.org/0000-0002-4322-0404
Schmidt, André P. https://orcid.org/0000-0001-5425-2180
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Funding
Funding for this research was provided by:
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Universidade Federal do Rio Grande do Sul
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul
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Article History
Received: 22 March 2025
Revised: 7 August 2025
Accepted: 25 August 2025
First Online: 1 September 2025
Declarations
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: All procedures adhered to the ethical guidelines for investigations of experimental pain in conscious animals [] and complied with the ARRIVE guidelines []. The minimum number of animals and intensity of noxious stimuli were used to achieve consistent results. All animal experiments were approved by the Ethics Committee on Animal Use (CEUA) of the Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil (ID: 30124).
: Not applicable, as this study did not involve human subjects.
: The authors declare no competing interests.
