Document is current

Article History

Received: 1 June 2020

Accepted: 17 March 2021

First Online: 16 May 2021

Declarations

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: Hugh Levaux, and Amit Shat, are employees of Protocol First. James Denmark is an employee of myClin. Ross L. Levine is on the Supervisory board of Qiagen, is on the SAB of Loxo (until 2019), Imago, Mission Bio, Mana, Auron, C4 Therapeutics and Isoplexis which include equity interest. He receives research support from and consulted for Celgene and Roche and consults for Incyte, Lilly, Janssen, Astellas, Morphosys and Novartis. He receives research support from Prelude. He has received honoraria from Astra Zeneca, Roche, Lilly and Amgen for invited lectures and from Gilead Sciences, Inc. for grant reviews. Melanie Owen, Spencer Kalk, Nicholas Kenny and Gene Vinson are employees of Syneos Healthcare. Alice Mims consulting (Ad Boards) for Jazz Pharmaceuticals, Abbvie/Genentech, Astellas, PTC Therapeutics, Novartis, Agios, and Syndax Therapeutics. Uma Borate consulting for Genetech, Daiichi Sankyo, Takeda, Pfizer, AbbVie/Genentech, and Novartis. William Blum reports commercial research support from Forma, Xencor, Celyad, and honoraria from AmerisourceBergen. Eytan Stein: Served on advisory boards for: Astellas, AbbVie, Genentech, Daiichi, Novartis, Amgen, Seattle Genetics, Syros, Syndax, Agios, Celgene. Equity Holder in Auron Therapeutics. Theophilus J. Gana is a Clinical Consultant to Leukemia & Lymphoma Society. Equity stake in Bausch Health. Brian J.Drucker: potential competing interests – SAB: Aileron Therapeutics, Therapy Architects (ALLCRON), Cepheid, Vivid Biosciences, Celgene, RUNX1 Research Program, EnLiven Therapeutics, Gilead Sciences (inactive), Monojul (inactive); SAB & Stock: Aptose Biosciences, Blueprint Medicines, Iterion Therapeutics, Third Coast Therapeutics, GRAIL (SAB inactive); Scientific Founder: MolecularMD (inactive, acquired by ICON); Board of Directors & Stock: Amgen; Board of Directors: Burroughs Wellcome Fund, CureOne; Joint Steering Committee: Beat AML LLS; Founder: VB Therapeutics; Clinical Trial Funding: Novartis, Bristol-Myers Squibb, Pfizer; Royalties from Patent 6958335 (Novartis exclusive license) and OHSU and Dana-Farber Cancer Institute (one Merck exclusive license). John Byrd—Research support from: Janssen; Genentech; Acerta; Pharmacyclics; Advisory Board: Syndax; National Cancer Institute (R35 CA197734, JCB) and in part through the NIH/NCI Cancer Center Support Grant P30 CA008748. Len Rosenberg, Ashley Yocum, Sonja Marcus, and Amy Burd are employees of LLS. LLS receives funding from: AbbVie, Agios Pharmaceuticals, Inc., Alexion Pharmaceuticals, Amgen, Astellas, Inc., AstraZeneca, Boehringer Ingelheim International GmbH, Boston Biomedical, Inc., Bristol-Myers Squibb, Celgene Corporation, Genentech, Gilead Sciences, Inc., ImmunoGen, Jazz, Johnson & Johnson, Novartis, Pfizer, Pharmacyclics, RTI Health, Shire, and Takeda Pharmaceutical Company Ltd. Nyla Hereema, Jo-Anne Vergilio, Mona Stefanos, and Abigail Shoben have nothing to disclose.