Wang, Hongbo https://orcid.org/0000-0003-3296-7198
Zhao, Xianda https://orcid.org/0009-0007-1631-2622
Hu, Suwen https://orcid.org/0009-0005-8613-9592
Zhao, Xiyue https://orcid.org/0000-0002-1549-6120
Wang, Liangrong https://orcid.org/0000-0003-0957-3756
Funding for this research was provided by:
Wenzhou Association for Science and Technology Service Project for Technological Innovation (KJFW0241)
General project of Zhejiang Health and Pharmaceutical Science and Technology Plan (2025KY466)
Article History
Received: 28 June 2025
Revised: 21 October 2025
Accepted: 28 October 2025
First Online: 6 January 2026
Declarations
:
: This study was approved by the Institutional Review Board of the First Affiliated Hospital of Wenzhou Medical University (approval number: KY2023-193) on 31 August 2023 and registered with the Chinese Clinical Trial Registry (No. ChiCTR2300078552) on 12 December 2023. The study was conducted in accordance with the Declaration of Helsinki and written informed consent was obtained from every participant.
: Not applicable.
: The authors declare that they have no conflicts of interest.