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Therapeutic potential of canagliflozin in DEN/TAA-induced renal cancer: mechanistic insights into NLRP3/IL-6/STAT3 and AMPK signaling and oxidative stress regulation

Crossref DOI link: https://doi.org/10.1007/s44446-025-00039-x

Published Online: 2025-10-09

Published Print: 2025-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Abdel-Rahman, Rehab F. https://orcid.org/0000-0002-4341-4954
Alsugoor, Mahdi H.

ALSuhaymi, Naif

Fayed, Hany M.

Mahmoud, Sawsan S.

Ibrahim, Fatma A.

Elbaset, Marawan A.
Funding

Funding for this research was provided by:

National Research Centre Egypt
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Text and Data Mining valid from 2025-10-01

Version of Record valid from 2025-10-09
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Article History

Received: 25 March 2025

Accepted: 3 August 2025

First Online: 9 October 2025

Declarations

:

: The experimental protocol was licensed (CU23052022441) by “Cairo University Institutional Animal Care and Use Committee” (IACUC).

: The authors state that they have no competing interests.

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