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Authors
Shah, Ankit
Maski, Manish
Li, Jiahua
Iff, Joel https://orcid.org/0000-0002-1102-0651
Nair, Rajeshwari
Gagnon-Sanschagrin, Patrick
Bedard, Jerome
Tuttle, Edward
Barber, Beth
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Funding
Funding for this research was provided by:
Vertex Pharmaceuticals
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Article History
Received: 1 May 2026
Accepted: 10 June 2026
First Online: 27 July 2026
Change Date: 22 August 2026
Change Type: Update
Change Details: This article was updated to add the visual abstract.
Declarations
Conflict of interest: AS, MM, JL, JI, RN, and BB are employees of Vertex Pharmaceuticals and own stock/stock options.PGS, JB, and ET are employees of Analysis Group, ULC/Inc., a consulting company that has provided paid consulting services to Vertex Pharmaceuticals, which funded the development and conduct of this study and manuscript.
Ethical approval: This was a retrospective study. This study used de-identified secondary data compliant with the Health Insurance Portability and Accountability Act (45 CFR § 164.514) and is therefore considered exempt from institutional review board review under 45 CFR § 46.104(d)(4).
