Calligaris, Matteo
Spanò, Donatella P.
Bonelli, Simone
Müller, Stephan A.
Carcione, Claudia
D’apolito, Danilo
Amico, Giandomenico
Miele, Monica
Di Bella, Mariangela
Zito, Giovanni
Nuti, Elisa
Rossello, Armando
Blobel, Carl P.
Lichtenthaler, Stefan F.
Scilabra, Simone D. http://orcid.org/0000-0001-7300-6153
Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (EXC 2145 SyNergy– ID 390857198)
Fondazione CON IL SUD (2018—PDR—00799)
National Institute of General Medical Sciences (R35 GM134907)
Article History
Received: 29 November 2023
Revised: 22 February 2024
Accepted: 4 March 2024
First Online: 4 April 2024
Declarations
:
: C. P. B. holds a patent on a method of identifying agents for combination with inhibitors of iRhoms. C. P. B. and the Hospital for Special Surgery have identified iRhom2 inhibitors and have co-founded the start-up company SciRhom in Munich to commercialize these inhibitors.
: This study was approved by our institute’s Ethics Committee, and informed consent obtained from all the voluntary participants. The anonymous blood donors received oral and written information about the possibility that their blood would be used for research purposes.