Hansen, Aleksander L. http://orcid.org/0000-0002-9514-8942
Thomsen, Reimar W. http://orcid.org/0000-0001-9135-3474
Brøns, Charlotte http://orcid.org/0000-0002-6653-9020
Svane, Helene M. L. http://orcid.org/0000-0002-1171-7694
Jensen, Rasmus T. http://orcid.org/0000-0002-4241-3394
Andersen, Mette K. http://orcid.org/0000-0001-8227-1469
Hansen, Torben http://orcid.org/0000-0001-8748-3831
Nielsen, Jens S. http://orcid.org/0000-0003-3179-1186
Vestergaard, Peter
Højlund, Kurt http://orcid.org/0000-0002-0891-4224
Jessen, Niels http://orcid.org/0000-0001-5613-7274
Olsen, Michael H. http://orcid.org/0000-0003-2230-5780
Sørensen, Henrik T. http://orcid.org/0000-0003-4299-7040
Vaag, Allan A. http://orcid.org/0000-0002-3690-2191
Funding for this research was provided by:
The Danish Agency for Science (09-067009, 09-075724)
Novo Nordisk Fonden (NNF17SA0030364, NNF17SA0030962-2, NNF20O0063292)
The Danish Diabetes Association
The Danish Health and Medicines Authority
Region of Southern Denmark
Lund University
Article History
Received: 26 January 2023
Accepted: 20 April 2023
First Online: 12 June 2023
Acknowledgements
: The authors are grateful to all participants in the DD2 study and to the healthcare personnel who recruited the participants at the general practices and outpatient clinics. The authors sincerely thank the DD2 management and the DD2 data managers. An abstract version of this study was presented at the EASD 2022 annual meeting in Stockholm, 22 September 2022.
: Danish data protection legislation does not allow sharing of the individual-level personal data used for this study. However, a data dictionary for variables used in the study and analysis code is in preparation and will be shared and made publicly available on the DD2 website, ExternalRef removed (expected in late 2023). Requests to access the Danish health registries used in this study can be sent from researchers at authorised research institutions to the Danish Health Data Authority by e-mail to forskerservice@sundhedsdata.dk. Requests to use the primary collected DD2 data can be made at ExternalRef removed.
: Open access funding provided by Lund University. The DD2 study was supported by the Danish Agency for Science (grant no. 09–067009 and 09–075724), the Danish Health and Medicines Authority, the Danish Diabetes Association, the Region of Southern Denmark, and the Novo Nordisk Foundation (grant no. NNF17SA0030962–2, NNF20O0063292 and NNF17SA0030364). Project partners are listed on the ExternalRef removed website. The study funders were not involved in the design of the study, the collection, analysis and interpretation of data, or writing the report. They did not impose any restrictions regarding publication of the report. The Department of Clinical Epidemiology, Aarhus University, receives funding for other studies in the form of institutional research grants to (and administered by) Aarhus University. None of these studies has any relation to the present study.
: CB owns stock in Novo Nordisk. MHO has received payment or honoraria for lectures, presentations or educational events from AstraZeneca and Boehringer Ingelheim, and has unpaid positions as chairperson of the Danish Hypertension Society and a Nucleus member of the Working Group for Prevention and Rehabilitation, Danish Society of Cardiology. The authors declare that there are no other relationships or activities that might bias, or be perceived to bias, their work.
: AAV conceived and designed the study and is the guarantor of the study. JSN was the principal manager of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2). ALH performed the statistical analysis, prepared the first draft of the manuscript, and revised the draft. All authors contributed to the interpretation of data and critically revised the content of the draft. AAV, RWT and HTS supervised the study. All authors read and approved the manuscript, and gave final approval of the version to be published. As such, they had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.