Wibaek, Rasmus http://orcid.org/0000-0002-4989-2084
Andersen, Gregers S. http://orcid.org/0000-0001-6125-300X
Linneberg, Allan http://orcid.org/0000-0002-0994-0184
Hansen, Torben http://orcid.org/0000-0001-8748-3831
Grarup, Niels http://orcid.org/0000-0001-5526-1070
Thuesen, Anne Cathrine B. http://orcid.org/0000-0002-8639-9117
Jensen, Rasmus T. http://orcid.org/0000-0002-4241-3394
Wells, Jonathan C. K. http://orcid.org/0000-0003-0411-8025
Pilgaard, Kasper A. http://orcid.org/0000-0003-2079-5229
Brøns, Charlotte http://orcid.org/0000-0002-6653-9020
Vistisen, Dorte http://orcid.org/0000-0001-5045-5351
Vaag, Allan A. http://orcid.org/0000-0002-3690-2191
Funding for this research was provided by:
Novo Nordisk Fonden (NNF18CC0034900)
Danish Diabetes and Endocrine Academy (NNF17SA0031406)
Lund University
Article History
Received: 28 January 2023
Accepted: 13 April 2023
First Online: 12 June 2023
Acknowledgements
: We thank the participants of the Inter99 cohort for their strong commitment to this research. We also thank senior statistician at Steno Diabetes Center Copenhagen, B. Carstensen, for his unreserved support with the statistical analysis. This study was presented as an abstract at the ADA, 82nd Scientific Sessions, 3–7 June 2022.
: Data supporting the findings of this study are available from Statistics Denmark (ExternalRef removed) and the Inter99 database (ExternalRef removed). Restrictions apply to the accessibility of these data, which were analysed under license for this study.
: This work was supported by a research grant from the Danish Diabetes Academy, which is funded by the Novo Nordisk Foundation (grant no. NNF17SA0031406) and Novo Nordisk Foundation Center for Basic Metabolic Research, which is an independent Research Center based at the University of Copenhagen, Denmark and partially funded by an unconditional donation from the Novo Nordisk Foundation (grant no. NNF18CC0034900). The funding sources were not involved in any part of this study and did not influence the decision to submit the paper for publication.
: DV, GSA and RW hold shares in Novo Nordisk A/S. DV has received research grants from Bayer A/S, Sanofi, Novo Nordisk A/S and Boehringer Ingelheim. The authors declare that there are no other relationships or activities that might bias, or be perceived to bias, their work.
: RW, AL, TH, KAP, CB, DV and AV designed the research. RW conducted the research. RW, GSA, JCKW and DV contributed to statistical analysis and interpretation of data. TH, NG, ACBT and RTJ performed genetic analysis. RW and AV wrote the paper. RW and AV had primary responsibility for the final content. All authors reviewed and approved the final manuscript. RW is guarantor of this study and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analyses.