Meek, Claire L. http://orcid.org/0000-0002-4176-8329
Stewart, Zoe A.
Feig, Denice S.
Furse, Samuel http://orcid.org/0000-0003-4267-2051
Neoh, Sandra L. http://orcid.org/0000-0001-9387-7079
Koulman, Albert http://orcid.org/0000-0001-9998-051X
Murphy, Helen R. http://orcid.org/0000-0002-5489-0614
,
Funding for this research was provided by:
Diabetes UK (DUK-HKF 17/0005712, PG 2017/2278)
Article History
Received: 30 March 2023
Accepted: 19 June 2023
First Online: 24 August 2023
Acknowledgements
: The authors would like to thank all the women with type 1 diabetes who participated in the CONCEPTT trial. We also acknowledge the invaluable support from the 31 clinical care teams and the CONCEPTT Steering Committee: D. S. Feig, H. R. Murphy, E. Asztalos, J. F. R. Barrett, R. Corcoy, A. de Leiva, L. E. Donovan, J. M. Hod, L. Jovanovic<sup>a</sup>, E. Keely, C. Kollman, R. McManus, K. E. Murphy, K. Ruedy and G. Tomlinson. For affiliations and other CONCEPTT contributors, see ESM Appendix InternalRef removed. <sup>a</sup>Dr Lois Jovanovic died during the preparation of this manuscript. Aspects of this study were presented in abstract form to the ADA Scientific sessions (2021; 2022), the Diabetes in Pregnancy Study Group (September 2021) and the EASD Annual Meeting (September 2021 and 2022). There are no overlapping manuscripts using this dataset in preparation, submitted or published.
: The data that support the findings of this study are available on request from the CONCEPTT trial steering committee via senior author HRM (Helen.Murphy@uea.ac.uk). The data are not publicly available as they contain information that could compromise research participant privacy/consent.
: This project was funded by Diabetes UK (PG 2017/2278). The CONCEPTT trial was funded by JDRF grants #17‐2011‐533, and grants under the JDRF Canadian Clinical Trial Network, a public–private partnership including JDRF and FedDev Ontario and supported by JDRF #80‐2010‐585. Medtronic supplied the CGM sensors and CGM systems at reduced cost. The study sponsor/funders were not involved in the design of the study; the collection, analysis and interpretation of data; writing the report; and did not impose any restrictions regarding the publication of the report. CLM is supported by the Diabetes UK Harry Keen Intermediate Clinical Fellowship (DUK-HKF 17/0005712), a BMA Foundation Award (Helen H. Lawson Award) and the European Foundation for the Study of Diabetes – Novo Nordisk Foundation Future Leaders’ Award (NNF19SA058974). HRM conducts independent research supported by the National Institute for Health and Care Research (NIHR) (Career Development Fellowship, CDF-2013-06-035) and is supported by Tommy’s charity. SF and AK acknowledge funding from the BBSRC (BB/M027252/1). DSF conducts independent research supported by the Canadian Institute for Health Research. This research was supported by the NIHR Cambridge BRC, the core biochemical assay laboratory (CBAL) and the core metabolomic and lipidomic laboratory (CMAL). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care.
: HRM is a member of the editorial board of Diabetologia. HRM has received honoraria for speaking engagements from Medtronic, Roche, Novo Nordisk, Eli-Lilly and is a member of the Medtronic European Advisory Board. CLM has received research support from Dexcom Inc. DSF is a member of the Novo Nordisk Expert Panel for the EXPECT trial and has received honoraria for speaking engagements from Medtronic. All other authors declare that there are no relationships or activities that might bias, or be perceived to bias, their contribution to this manuscript.
: CLM contributed to study design and formulated the data analysis plan, analysed and interpreted the data, made figures and tables, wrote and revised the manuscript. ZAS applied for funding, arranged the laboratory analyses and contributed to manuscript revisions. SLN collected dietary data, read and revised the final manuscript. SF and DSF contributed to data interpretation, manuscript writing and revisions. AK analysed and interpreted the data and reviewed and revised the manuscript. HRM contributed to study design, data interpretation and reviewed and revised the manuscript. All authors gave approval of the final version of the manuscript prior to publication. CLM is the guarantor of this work and, as such, has had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.