Gajecka, Marzena http://orcid.org/0000-0001-7468-2604
Gutaj, Pawel http://orcid.org/0000-0003-2885-9792
Jaskiewicz, Katarzyna http://orcid.org/0000-0002-6380-5119
Rydzanicz, Malgorzata http://orcid.org/0000-0002-6969-0535
Szczapa, Tomasz http://orcid.org/0000-0002-5214-2719
Kaminska, Dorota http://orcid.org/0000-0001-5934-1115
Kosewski, Grzegorz http://orcid.org/0000-0002-6380-7704
Przyslawski, Juliusz http://orcid.org/0000-0001-9205-2817
Ploski, Rafal http://orcid.org/0000-0001-6286-5526
Wender-Ozegowska, Ewa http://orcid.org/0000-0002-5492-8651
Funding for this research was provided by:
Poznan Supercomputing and Networking Center (PSNC-534)
Polish Diabetes Association (Professor Artur Czyżyk’ Scientific Grant 2015, Professor Artur Czyżyk’ Scientific Grant 2017)
Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu (502-01-01110142-05618, 502-14-03301402-09911)
Article History
Received: 25 July 2023
Accepted: 2 October 2023
First Online: 29 November 2023
Acknowledgements
: We thank the participants who took part in this study. MG was a recipient of a scholarship from the Kosciuszko Foundation (the Kosciuszko Foundation Exchange to the US Program, 2019–2020), with training carried out in the Department of Obstetrics & Gynecology at the Baylor College of Medicine, Houston, TX, USA. Special thanks to K. M. Aagaard and M. Jochum (Department of Obstetrics & Gynecology at the Baylor College of Medicine, Houston, TX, USA) for the opportunity to analyse the raw sequencing data for the assessed biological samples and their involvement in the generation of tables and figures for this project.
: The BioProject (PRJNA961636) and associated SRA metadata are available at ExternalRef removed. Processed data on probiotic supplementation and the PICRUSt analysis are available in the Mendeley Data Repository (ExternalRef removed).
: This study was supported by the Polish Diabetes Association, the Professor Artur Czyżyk’ Scientific Grants, 2015 and 2017 (to PG) and the Poznan University of Medical Sciences, grant no. 502-01-01110142-05618 (to EWO), grant no. 502-14-03301402-09911 (to DK), and budget no. 2762 (to MG). Computational calculations were partly performed at the Poznan Supercomputing and Networking Center (grant no. PSNC-534, to MG). The study funders were not involved in the design of the study, the collection, analysis and interpretation of the data or writing of the report, and did not impose any restrictions regarding the publication of the report.
: The authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.
: MG, EW-O, PG and RP designed the study. PG, EW-O and TS carried out participant recruitment and diagnosis. PG, EW-O, TS, DK and GK participated in sample collection and the participant surveys. PG, KJ, DK, TS and MG generated the metadata. KJ extracted the microbial DNA and generated the 16S rRNA libraries. MR and KJ generated and processed the raw sequencing data. MG and KJ performed the data analysis. MG, KJ, PG and EW-O interpreted the data. GK and JP performed the nutritional assessment. KJ and MG generated the figures and MG and KJ wrote the paper. All authors contributed to critical revisions and approved the final version for publication. MG is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.