Ampofo, Emmanuel http://orcid.org/0000-0002-1886-5657
Pack, Mandy
Wrublewsky, Selina
Boewe, Anne S.
Spigelman, Aliya F.
Koch, Hanna
MacDonald, Patrick E.
Laschke, Matthias W. http://orcid.org/0000-0002-7847-8456
Montenarh, Mathias http://orcid.org/0000-0002-3777-382X
Götz, Claudia http://orcid.org/0000-0001-7115-0485
Funding for this research was provided by:
Dr. Rolf M. Schwiete Stiftung, Mannheim, Germany (project Nr. 2020 – 006)
Universität des Saarlandes
Article History
Received: 3 August 2023
Accepted: 7 February 2024
First Online: 20 March 2024
Acknowledgements
: The authors thank Servier Medical Art for providing access to designed medical elements (ExternalRef removed), supporting the generation of graphical items in this publication. We are grateful for the excellent technical assistance of C. Bickelmann (Institute for Clinical & Experimental Surgery). We thank the Human Organ Procurement and Exchange (HOPE) programme and Trillium Gift of Life Network (TGLN) for their work in procuring human donor pancreas for research, and J. Lyon and N. Smith (Department of Pharmacology and Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada) for their efforts in human islet isolation. We especially thank the organ donors and their families for their kind gift in support of diabetes research.
: Data sets are available upon reasonable request from the corresponding author.
: This research was funded by the Dr. Rolf M. Schwiete Stiftung, Mannheim, Germany, project No. 2020–006 to CG.
: PEM is an Associate Editor for <i>Diabetologia</i>. He had no involvement in handling of, or review of, this paper. The other authors declare that there are no relationships or activities that might bias, or be perceived to bias, their work.
: EA, CG, MP, MM, PEM and MWL designed and conceptualised the study. EA, CG, MP, SW, HK, AFS and ASB designed and performed experiments, and collected and analysed data. EA, MP, SW, AFS and CG prepared figures. EA and CG wrote the manuscript. PEM, MWL and MM interpreted data, and provided essential material and conceptual advice. CG acquired funding. CG, MM and EA supervised the study. MP, SW, MWL, ASB, HK, AFS, PEM and MM revised the manuscript. All authors have read and approved the manuscript. CG is responsible for the integrity of the work as a whole.