Kanehisa, Masayuki
Terao, Takeshi
Shiotsuki, Ippei
Kurosawa, Keiko
Takenaka, Ryuichi
Sakamoto, Teruo
Shigemitsu, Osamu
Ishii, Nobuyoshi
Hatano, Koji
Hirakawa, Hirofumi
Funding for this research was provided by:
Japanese Society for the Promotion of Science (15K09838)
Article History
Received: 29 June 2017
Accepted: 23 August 2017
First Online: 28 August 2017
Compliance with ethical standards
: This study was approved by the ethical committee of Oita University Faculty of medicine, and all subjects provided written informed consent. The authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the Helsinki Declaration of 1975, as revised in 2008.
: Takeshi Terao served as a consultant to GlaxoSmithKline; he has received lecture fees from Eli Lilly, Pfizer, Otsuka, Mochida, Taisho-Toyama, MSD, Shionogi, Astellas, Daiichi-sankyo, and Meiji; and grants from Pfizer, Otsuka, Mochida, MSD, Astellas, Shionogi, Daiichisankyo, Tanabe-Mitsubishi, and Meiji. The other authors declare no conflict of interest.