Carbone, Laura D.
Bůžková, Petra
Fink, Howard A.
Robbins, John A.
Bethel, Monique
Hamrick, Mark W.
Hill, William D. http://orcid.org/0000-0002-8033-1605
Funding for this research was provided by:
National Heart, Lung, and Blood Institute (HHSN268201200036C)
National Institute on Aging (R01AG023629)
Augusta University (Pilot Study Research Program)
U.S. Department of Veterans Affairs (1I01CX000930-)
Article History
Received: 5 October 2016
Accepted: 30 January 2017
First Online: 28 February 2017
Compliance with Ethical Standards
:
: Laura D. Carbone, Petra Bůžková, Howard A. Fink, John A. Robbins, Monique Bethel, Mark W. Hamrick and William D. Hill declare that they have no conflict of interest.
: William Hill has received a Utility Patent. GRU OTT 2013-26 U.S.S.N. 61/712/708 filed 2-22-2013. Publication# US-2014-0288010-A1. The application was published on September 25, 2014. “Compositions and Methods for Increasing Stem Cell Survival” By William D. Hill, Samuel Herberg, & Sudharsan Periyasami-Thandavan. Describing SDF-1’s role in enhancing BMSC autophagy and blocking apoptosis and potential clinical applications, and including inhibition of DPP4 to enhance SDF-1 activity levels.
: The institutional review board (IRB) at each site approved the CHS methods, and all participants gave written informed consent. Augusta University’s Office of Human Research Protection Assurance approved the use of human plasma samples previously collected as part of the CHS. No animals were used.