Lukey, Pauline T.
Coello, Christopher
Gunn, Roger
Parker, Christine
Wilson, Frederick J.
Saleem, Azeem
Garman, Nadia
Costa, Maria
Kendrick, Stuart
Onega, Mayca
Kang’ombe, Arthur R.
Listanco, Allan
Davies, James
Ramada-Magalhaes, Joaquim
Moz, Sara
Fahy, William A.
Maher, Toby M.
Jenkins, Gisli
Passchier, Jan
Marshall, Richard P.
Article History
Received: 25 July 2019
Accepted: 16 October 2019
First Online: 9 December 2019
Compliance with ethical standards
:
: This study was sponsored by GlaxoSmithKline R&D (study numbers 200262/ NCT02612051). GlaxoSmithKline reviewed the manuscript for factual accuracy.FJW is an employee and shareholder of GSK. He was previously a consultant to ECNP R&S, GlaxoSmithKline, IPPEC, King’s College London, Lundbeck A/S, Mentis Cura ehf and Pfizer Inc. and has received travel expenses as a guest speaker from Orion Pharma Ltd.PTL was a GlaxoSmithKline employee at the time of the study and is currently a shareholder. She now works or has worked as an independent consultant to GlaxoSmithKline R&D, the Francis Crick Institute, Galecto, Mereo BioPharma, Peptinnovate, BerGenBio, LifT BioSciences, Afortiori, Morphic Therapeutics.TMM has, via his institution, received industry-academic funding from GlaxoSmithKline R&D and UCB and has received consultancy or speaker’s fees from Apellis, Astra Zeneca, aTyr Pharma, Bayer, Biogen Idec, Boehringer Ingelheim, Galapagos, GlaxoSmithKline R&D, ProMetic, Roche, Sanumed and UCBGJ has, via his institution, received industry-academic funding from Biogen, Galecto, GlaxoSmithKline R&D and MedImmune and has received consultancy or speaker’s fees from, Boehringer Ingelheim, Galapagos, GlaxoSmithKline R&D, Heptares, MedImmune, Pliant, Roche.ARK is an employee of GlaxoSmithKline. WAF, CP, NG, SK are employees of GlaxoSmithKline and hold shares. MC and RPM were employees of GlaxoSmithKline at the time of the study.AL, CC, JRM and MO have no conflicts of interest to declare.RG, JD, SM, AS, JP are employees of Invicro and received funding from GSK for the conduct of this study. RG has also received consultant fees from AbbVie, Biogen and Cerveau. AS holds GSK shares.
: All procedures performed in this study were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments.
: Informed consent was obtained from all individual participants included in the study.