Liu, Qiaofei http://orcid.org/0000-0001-9889-2833
Wu, Huanwen
Li, Yuan
Zhang, Ronghua
Kleeff, Jorg
Zhang, Xiang
Cui, Ming
Liu, Jingkai
Li, Tong
Gao, Junyi
Pan, Boju
Wu, Wenming
Wang, Weibin
Zhou, Li
Guo, Junchao
Dai, Menghua
Zhang, Taiping
Liao, Quan
Lu, Zhaohui
Zhao, Yupei
Funding for this research was provided by:
National Natural Science Foundation of China (81560387, 81673023, 81872501, 81272573, 81502068)
Beijing Natural Science Foundation of China (7172177)
CAMS innovation Fun for Medical Sciences (NWA0564-3)
Article History
Received: 3 May 2019
Accepted: 3 March 2020
First Online: 13 April 2020
Compliance with ethical standards
:
: All of the authors declared there was no conflict of interest.
: This study was a retrospective study and was approved by the Ethics Committee of Peking Union Medical College Hospital and was registered at ClinicalTrials.org (NCT02654288).
: All of the patients signed the informed consent to donate samples for scientific research. In this study, only resected tumor and peritumor sample were used; therefore, there were nearly no potential harms to the patients.
: Male 4-week-old or 8-week-old C57BL/6 J mice were purchased from VITAL RIVER Animal Center (Beijing, China). Animal studies were performed in accordance with the institutional guidelines of Peking Union Medical College Hospital and was approved by animal study committee of Peking Union Medical College Hospital on December 1, 2014.
: All cell lines were purchased from Cell Line Bank of Chinese Academy of Medicine Sciences.