Oka, Naoto http://orcid.org/0000-0003-4352-7606
Markova, Tzvetanka
Tsuzuki, Kenzo
Li, Wen
El-Darawish, Yosif
Pencheva-Demireva, Magdalena
Yamanishi, Kyousuke
Yamanishi, Hiromichi
Sakagami, Masafumi
Tanaka, Yoshimasa
Okamura, Haruki
Funding for this research was provided by:
Japan Society for the Promotion of Science, KAKENHI (JP25462671, JP16K11220)
Japan Agency for Medical Research and Development (JP18nk0101355h0102)
Article History
Received: 20 March 2019
Accepted: 19 March 2020
First Online: 24 April 2020
Compliance with ethical standards
:
: The authors declare that they have no conflict of interest.
: All mouse experiments were conducted in line with the Guide for the Care and Use of Laboratory Animals published by the National Institutes of Health and guidelines provided by the European Parliament for the protection of animals. All mice were bred and maintained at our animal facility in accordance with the guidelines for the care and use of experimental animals at the Hyogo College of Medicine, Japan. All experiments were conducted with approval (#28041, #15-029, #16-021, #16-030, #16-034, #17-018 and #19-017) from the Animal Care Committee of the Hyogo College of Medicine.
: WT mice were purchased from SLC Japan Co, Ltd. (Shizuoka, Japan). C57BL/6 J IFN-γKO male mice (9 weeks old) were purchased from Jackson Laboratory (Bar Harbor, ME, USA). C57BL/6JN IL-18KO male mice were backcrossed for more than eight generations at the National Institute for Agrobiological Sciences (Ibaraki, Japan). Homozygous mutant mice were used for breeding and experiments at the animal facilities of the Hyogo College of Medicine.
: Murine YAC-1 was obtained from the American Type Culture Collection (Manassas, VA, USA). Authentication of the cell line was not required as cells were purchased from professional cell line vendor and our master cell banks were generated soon after placing the original vials of cells into culture.