Sorski, Liat
Melamed, Rivka
Levi, Ben
Matzner, Pini
Lavon, Hagar
Rosenne, Ella
Shaashua, Lee
Ricon, Itay
Sandbank, Elad
Benbenishty, Amit
Ben-Eliyahu, Shamgar
Funding for this research was provided by:
National Institute of Mental Health (CA125456)
Israel-USA bi-national Science Foundation (2005331)
Article History
Received: 24 August 2019
Accepted: 27 April 2020
First Online: 13 May 2020
Compliance with ethical standards
:
: The authors declare that they have no conflict of interest.
: The Institutional Animal Care and Use Committee of Tel Aviv University approved all studies.
: CT26 – P-13-014, MC38 – 10-18-007.
: BALB/c male and female mice and C57B1/6j male and female mice were purchased from Harlan laboratories (Jerusalem, Israel) at the age of 4 weeks. Animals were housed 3–4 per cage at 22 ± 1 °C, on a 12:12 light/dark cycle and were allowed ad libitum access to food and water. Animals were used at the age of 8–12 weeks. (Animals were age-matched between groups within each experiment.)
: <i>The CT26 tumor cell line</i>: CT26 tumor cells were kindly provided by Prof. Eliezer Flesher (Department of Human Microbiology, Faculty of Medicine, Tel Aviv University).
: The MC38 murine colon adenocarcinoma was derived from tumor that arose in C57B1/6 mice. Tumor cells were kindly provided by Dr. Eran Nizri (Tel Aviv Sourasky Medical center).