Received: 4 June 2020
Accepted: 6 January 2021
First Online: 2 February 2021
Compliance with ethical standards
: The authors declare that they have no conflict of interest.
: The study on CRC patients was approved by the SingHealth Centralised Institutional Review Board (CIRB Ref: 2017/3058). All healthy donor blood sample collections and procedures used in this study were approved by the Institutional Review Board of Singapore in accordance with the guidelines of the Health Sciences Authority of Singapore (Reference No: 201906-06).
: Informed consent was obtained from all participants included in the study in accordance with the Declaration of Helsinki.
: The authors affirm that human research participants provided informed consent for publication of all data, results, and images.