Schrezenmeier, Hubert http://orcid.org/0000-0003-1222-6659
Röth, Alexander
Araten, David J.
Kanakura, Yuzuru
Larratt, Loree
Shammo, Jamile M.
Wilson, Amanda
Shayan, Gilda
Maciejewski, Jaroslaw P.
Funding for this research was provided by:
Alexion Pharmaceuticals (PNH Registry)
Article History
Received: 28 May 2019
Accepted: 21 April 2020
First Online: 10 May 2020
Compliance with ethical standards
:
: Hubert Schrezenmeier has received honoraria and research support (both to University of Ulm) from Alexion Pharmaceuticals, Inc., and honoraria (to University of Ulm) from Ra Pharma, Roche, and Alnylam Pharmaceuticals. Alexander Röth has received honoraria and consulting fees from Alexion Pharmaceuticals, Inc., Roche, and Novartis, and research support from Alexion Pharmaceuticals, Inc., and Roche. David J. Araten has received honoraria and consulting fees from Alexion Pharmaceuticals, Inc. Yuzuru Kanakura has received honoraria and research support from Alexion Pharmaceuticals, Inc. Loree Larratt has received honoraria and research support (for the laboratory at the University of Alberta, for ADAMTS13 testing) from Alexion Pharmaceuticals, Inc. Jamile M. Shammo has received honoraria, consulting fees, and research support from Alexion Pharmaceuticals, Inc. Amanda Wilson and Gilda Shayan are former employees and stockholders of Alexion Pharmaceuticals, Inc. Jaroslaw P. Maciejewski has received consulting fees from Alexion Pharmaceuticals, Inc., Apellis Pharmaceuticals, and Ra Pharma; has also received speaker fees from Alexion Pharmaceuticals, Inc. and is a member of the Executive Committee of International PNH Registry for Alexion Pharmaceuticals, Inc.
: The Registry protocol was approved by an ethics committee for each site, and the Registry is being conducted in compliance with the International Council for Harmonisation Guideline for Good Clinical Practice.
: The institutional review boards (or equivalent) of participating centers approved the Registry, and written informed consent was provided by all patients before study entry.