Fedkov, Dmytro http://orcid.org/0000-0001-7965-9438
Berghofen, Andrea http://orcid.org/0000-0001-8306-0129
Weiss, Christel http://orcid.org/0000-0002-8692-5690
Peine, Christine http://orcid.org/0000-0001-6500-7180
Lang, Felix http://orcid.org/0000-0001-6102-2674
Knitza, Johannes http://orcid.org/0000-0001-9695-0657
Kuhn, Sebastian http://orcid.org/0000-0002-8031-2973
Krämer, Bernhard K. http://orcid.org/0000-0002-1718-2918
Leipe, Jan http://orcid.org/0000-0001-9684-9700
Funding for this research was provided by:
Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg (42.04HV.MED(18)/25/1)
Article History
Received: 1 June 2022
Accepted: 20 July 2022
First Online: 16 September 2022
Declarations
:
: DF, FL, and CP are employees and have an equity interest in Midaia GmbH and have no other disclosures to make. Midaia GmbH developed a mobile application that was used in this study but did not finance this study. JK received financial support from ABATON GmbH, developer of software for rheumatic diseases. SK is founder and managing partner of MED.digital GmbH. He is member of the “Digitalization of health care “ and “Medical Education and University Medicine” committees of the German Medical Association. JL, AB, CW, BK declare that they have no conflict of interest. The investigator (JL) and his respective research team collected all the data. Statistical analyses were conducted by a biostatistician (CW) at Heidelberg University following a prespecified statistical analysis plan.
: The study was conducted in accordance with the ethical principles of the Declaration of Helsinki and Good Clinical Practice guidelines and was approved by the appropriate institutional review boards (Ethics Committee of Medical Faculty Mannheim, Heidelberg University, protocol #2020-418 M-§23b, 26 Dec 2020). Authors fulfilled the ICMJE authorship criteria.
: Written informed consent was obtained from all patients prior to study start.