Yoo, Roh-Eul
Yun, Tae Jin http://orcid.org/0000-0001-8441-4574
Hwang, Inpyeong
Hong, Eun Kyoung
Kang, Koung Mi
Choi, Seung Hong
Park, Chul-Kee
Won, Jae-Kyung
Kim, Ji-hoon
Sohn, Chul-Ho
Funding for this research was provided by:
Seoul National University Hospital (04-2015-0690)
Article History
Received: 8 April 2019
Revised: 9 July 2019
Accepted: 19 July 2019
First Online: 29 August 2019
Compliance with ethical standards
:
: The scientific guarantor of this publication is Tae Jin Yun.
: The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.
: One of the authors (R.E.Y.) has significant statistical expertise.
: Requirement for informed consent was waived due to its retrospective nature.
: Institutional Review Board approval was obtained.
: Part of the patient population in this study (<i>n</i> = 132) overlaps with those in a previous study (Hong EK, Choi SH, Shin DJ et al (2018) Radiogenomics correlation between MR imaging features and major genetic profiles in glioblastoma. Eur Radiol. ExternalRef removed). The current study differs from the previous study in that we used ASL-PWI to conduct rigorous radiogenomics and survival analyses, focusing on both enhancing and nonenhancing portions of tumors. Moreover, the current study expands on the prior study by having a larger patient number and includes a more in-depth survival analysis using a multivariable survival model based on various imaging, molecular, and clinical predictors.
: • retrospective• diagnostic or prognostic study• performed at one institution