Funding for this research was provided by:
Fondazione Cassa di Risparmio di Cento
Received: 20 November 2019
Revised: 5 February 2020
Accepted: 28 February 2020
First Online: 12 March 2020
Compliance with ethical standards
: The scientific guarantor of this publication is Maurizio Grosso.
: The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.
: One of the authors has significant statistical expertise.
: Written informed consent was obtained from all subjects (patients) in this study.
: Institutional Review Board approval was obtained.
: Some study subjects or cohorts have been previously reported in the results of the SOS study which have already been published as specified in the references. This study focuses on the application of AI to the data obtained during the trial.
: • Prospective• Diagnostic or prognostic study• Performed at one institution