Hernando, Diego http://orcid.org/0000-0002-0016-0317
Cook, Rachel J.
Qazi, Naila
Longhurst, Colin A.
Diamond, Carol A.
Reeder, Scott B.
Funding for this research was provided by:
National Institute of Diabetes and Digestive and Kidney Diseases (R01 DK100651, K24 DK102595, R01 DK083380, R01 DK117354)
Wisconsin Alumni Research Foundation (WARF Accelerator Program)
Article History
Received: 3 March 2020
Revised: 5 June 2020
Accepted: 30 July 2020
First Online: 12 August 2020
Compliance with ethical standards
:
: The scientific guarantor of this publication is Diego Hernando, PhD.
: The authors of this manuscript declare relationships with the following companies: Dr. Hernando is a cofounder of Calimetrix. Dr. Reeder consults for ArTara Therapeutics and HeartVista. Dr. Reeder is a cofounder of Calimetrix.
: One of the coauthors (Colin Longhurst, MS, UW Department of Biostatistics and Medical Informatics) has significant statistical expertise.
: Written informed consent was obtained from all subjects (patients) in this study.
: Institutional Review Board approval was obtained.
: Some study subjects or cohorts have been previously reported. Hernando et al (Magnetic resonance in medicine 70 (3), 648–656) demonstrated the feasibility of quantifying liver iron concentration from measured B0 field maps. Sharma et al (Magnetic resonance in medicine 74 (3), 673–683) validated a method for quantitative susceptibility mapping in the liver. Horng et al (Journal of Magnetic Resonance Imaging 45 (2), 428–439) evaluated the accuracy of a single-R2* signal model for fat quantification in the presence of liver iron overload.
: • prospective• cross-sectional• single-institution study.