Funding for this research was provided by:
National Natural Science Foundation of China (81872475, 81372413)
National Natural Science Foundation of China (81871439, 61801474)
Shandong Key Research and Development Plan (2017CXGC1209, 2017GSF18164)
Guangdong Provincial Key Research and Development Program (2019B010152001)
Chinese Academy of Sciences-Iranian Vice Presidency for Science and Technology Silk Road Science Fund (GJHZ1857)
Science and Technology Plan Projects of Jiangsu (BE2019665)
Outstanding Youth Natural Science Foundation of Shandong Province (JQ201423)
Jinan Clinical Medicine Science and Technology Innovation Plan (201704095)
National Key Research and Development Program of China (2016YFC0904700)
Received: 12 October 2020
Revised: 20 July 2021
Accepted: 8 August 2021
First Online: 26 September 2021
: The scientific guarantor of this publication is Shuanghu Yuan.
: The authors of this manuscript declare no relationships with any companies whose products or services may be related to the subject matter of the article.
: Jiayi Zhang kindly provided statistical advice for this manuscript.
: Written informed consent was obtained from all subjects (patients) in this study.
: Institutional Review Board approval was obtained.
: • retrospective• randomized controlled trial• performed at one institution