Chu, Philip W.
Kofler, Cameron
Haas, Brian
Lee, Choonsik
Wang, Yifei
Chu, Cameron A.
Stewart, Carly
Mahendra, Malini
Delman, Bradley N.
Bolch, Wesley E.
Smith-Bindman, Rebecca http://orcid.org/0000-0003-1972-639X
Funding for this research was provided by:
Foundation for the National Institutes of Health (R01-CA181191)
Patient-Centered Outcomes Research Institute (CD-1304-7043, DI-2018C1-11375)
Article History
Received: 8 March 2023
Revised: 4 August 2023
Accepted: 9 August 2023
First Online: 6 October 2023
Declarations
:
: The scientific guarantor of this publication is Rebecca Smith-Bindman.
: The authors of this manuscript declare relationships with the following companies: Dr. Smith-Bindman is a co-founder of Alara Imaging, a company focused on collecting and reporting radiation dose and imaging quality information for computed tomography. Alara had no role in the study, and Dr. Smith-Bindman has not received funding from Alara Imaging. Other authors have no relationships with Alara and no conflicts of interests relevant to this article to disclose.
: Multiple authors have significant statistical expertise, and no complex statistical methods were necessary for this paper.
: The UCSF Committee on Human Research provided a waiver of individual informed consent. Collaborating institutions obtained local Institutional Review Board approval or relied on the UCSF approval to contribute data to the Registry.
: Institutional Review Board approval was not required because the paper uses anonymized data.
: Some study subjects or cohorts overlap with several studies that use the same dose registry, but for different purposes, including:Chu PW, Yu S, Wang Y, et al Reference phantom selection in pediatric computed tomography using data from a large, multicenter registry. Pediatr Radiol. 2022 Mar;52(3):445–452. ExternalRef removed. Epub 2021 Dec 6. PMID: 34866159; PMCID: PMC8857172.Smith-Bindman R, Chu P, Wang Y, et al Comparison of the effectiveness of single-component and multicomponent interventions for reducing radiation doses in patients undergoing computed tomography: a randomized clinical trial. JAMA Intern Med. 2020 May 1;180(5):666–675. ExternalRef removed. PMID: 32227142; PMCID: PMC7105953.Smith-Bindman R, Wang Y, Chu P, et al International variation in radiation dose for computed tomography examinations: prospective cohort study. BMJ. 2019 Jan 2;364:k4931. ExternalRef removed. PMID: 30602590; PMCID: PMC6314083.The CT data derive from the UCSF International CT Dose Registry, some parts of which have been used in prior publications, including approximately 1 million CTs in a randomized trial to assess whether participation in a learning collaborative results in meaningful reduction in radiation doses.
: • prospective• observational• multicenter study